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. 2021 Jun 14;8:668340. doi: 10.3389/fmolb.2021.668340

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Copyright © 2021 Parra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Graphic representation of a distance matrix using a chord diagram showing the flows or connections between the markers included in a multiplex immunofluorescence panel. The chord diagram shows various connections between markers that generate cell phenotypes from a multiplex immunofluorescence panel; these markers include cytokeratin (CK), CD3, CD8, FOXP3, PD-1, PD-L1, KI67, and CD68. The graphic was generated using R studio software version 3.6.1.