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. 2021 Jun 11;11:654685. doi: 10.3389/fonc.2021.654685

Table 1.

Clinical characteristics of patients with bladder cancer.

Characteristics Training cohort*(n=293) Internal validation cohort (n=73) External validation cohort (n=75) p-value
Age 0.038
Median (IQR) 65 (56,72) 68 (61,74) 65 (59,77)
Gender 0.166
Female 75 (25.6) 13 (17.8) 13 (17.3)
Male 218 (74.4) 60 (82.2) 62 (82.7)
CT-reported number of lesions 0.016
Unifocal 229 (78.2) 66 (90.4) 54 (72.0)
Multifocal 64 (21.8) 7(9.6) 21 (28.0)
CT-reported largest lesion diameter (cm) 0.063
Mean ± SD 2.71 ± 1.67 2.33 ± 1.62 2.78 ± 1.70
≤3 188 (64.2) 57 (78.1) 52 (69.3)
>3 105 (35.8) 16 (21.9) 23 (30.7)
CT attenuation of the largest lesion (HU) 0.030
Mean ± SD 67.1 ± 14.0 56.3 ± 20.9 70.5 ± 13.0
Pathologic T stage 0.010
≤T1 217 (74.1) 58 (79.5) 44 (58.7)
≥T2 76 (25.9) 15 (20.5) 31 (41.3)

*The training cohort (n=293) is the combination of the development (n=183) and tuning (n=110) cohorts. IQR, interquartile; SD, standard deviation.