Figure 1.

Illustration of analytical procedure. Illustration of our analytical procedure using one dlPFC locus as exemplar. First, the whole brain functional connectivity maps for each subject was calculated using the example dlPFC locus as seed. By combining these functional connectivity maps with the post-treatment information obtained during the follow-up period, we utilized the Cox regression based modelling to predict cocaine relapse. This procedure was conducted recursively for all 98 dlPFC sub-regions covering the entire bilateral dlPFC area.