FIGURE 2.

Phenotypes of embryos and oocytes from control and patients. (A) Phenotype of control embryos from a subject underwent the ICSI attempt owing to male infertility and embryos from the patient II-4 in family 1. The light microscope was used to observe the morphologies of embryos on days 1, 2, 3, and 5 during cultivation. (B) The morphologies and immunofluorescence staining results of an oocyte from the patient II-4 in family 1 and a normal oocyte from a control individual. Oocytes were stained with DAPI (blue) in order to visualize the DNA and immunolabeled with antibodies against TLE6 (green). Scale bar, 20 μm.