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. 2021 Jun 11;9:690522. doi: 10.3389/fcell.2021.690522

FIGURE 4.

FIGURE 4

The interaction between XIST and miRNAs as well as their targets in pancreatic cancer cells (Liang et al., 2017; Wei et al., 2017; Sun et al., 2018; Shen et al., 2019; Sun and Zhang, 2019; Liu et al., 2020; Zou et al., 2020). XIST interaction with miR-140 and miR-124 increases expression of iASPP and promotes growth of pancreatic cancer cells (Liang et al., 2017). XIST also enhances expression of TGF-β2 through sequestering miR-141-3p. This interaction enhances invasiveness of pancreatic cancer cells (Sun and Zhang, 2019).