TABLE 2.

Diagnostic value of XIST in cancers.

Cancer type	Numbers of clinical samples	Distinguish between	Area under curve	Sensitivity (%)	Specificity (%)	References
Nasopharyngeal carcinoma (NPC)	108 pairs of NPC tissues and ANTs	NPC patients vs. controls	0.813	0.886	0.795	Song et al., 2016
Early gastric cancer (EGC)	76 pairs of EGC tissues and ANTs and EGC plasma	EGC patients vs. controls	0.733	0.846	0.590	Lu et al., 2017
Colorectal cancer	120 serum specimens from CRC responding and non-responding patients to 5FU treatment	CRC patients showing response to 5FU treatment vs. patients showing no response	0.717	0.756	0.683	Xiao et al., 2017
	Serum EVs from 94 CRC patients and 41 healthy participants	CRC patients vs. healthy controls	0.864	0.883	0.902	Yu et al., 2020
Non-small cell lung cancer	32 pairs of NSCLC tumor tissues and ANTs 64 serum samples	NSCLC vs. controls	0.834	0.726	0.935	Tantai et al., 2015
Breast cancer	36 serum samples from breast cancer patients and 32 control healthy subjects	Breast cancer patients vs. healthy controls	0.78	0.67	0.89	Zhao et al., 2018
Thyroid cancer	77 pairs of thyroid cancer tissue samples and ANTs	Thyroid cancer patients vs. healthy controls	0.7360	–	–	Liu et al., 2018