Figure 4.

Subcellular localization and cytonuclear interactions of ERC hits. Proteins encoded by genes exhibiting signatures of coevolution with plastome partitions were analyzed for their localization and interactions as classified by the CyMIRA database (Forsythe et al., 2019). Categories indicating “interacting” refer to nucleus-encoded proteins predicted to directly physically interact with organelle-encoded proteins. The number of total genes in each category is indicated in parentheses. Statistical significance of enrichment/depletion (Fisher’s exact test) is indicated by filled points (P <0.05).