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. 2021 Feb 2;33(4):917–939. doi: 10.1093/plcell/koab030

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© The Author(s) 2021. Published by Oxford University Press on behalf of American Society of Plant Biologists.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Ratio distributions of gene expression in each tetrasomy compared with diploids (4D/2D) or trisomies (4D/3D). Analysis was conducted as described in Figure 1. Ratios of 2.0 (4D/2D) and 1.33 (4D/3D) represent a gene-dosage effect in cis, whereas 1.0 represents dosage compensation. Ratios of 0.5 (4D/2D) and 0.75 (4D/3D) represent the inverse ratio of gene expression in trans, whereas 1.0 represents no change. Ratios of 2.0 (4D/2D) and 1.33 (4D/3D) represent a positive modulation in trans. These ratio values are demarcated with labeled vertical lines in red (0.5), orange (0.75), black (1.0), blue (1.33), and purple (2.0).