Table 1.
Baseline clinical characteristics of patients with well-controlled primary hypertension.
| All n=142 | HADS-A (<7) low HT group n=80 | HADS-A(≥7) high HT group n=62 | P value | |
|---|---|---|---|---|
| Age (years) | 53.7±11 | 53.6±11.1 | 53.9±11 | 0.91 |
| Gender (male) (n,%) | 57 (40.1) | 32 (40) | 25 (40.3) | 0.97 |
| Pre-weight (kg) | 78.8±12.8 | 78.5±12.9 | 79.1±12.7 | 0.76 |
| Pre-BMI (kg/m2) | 28±4.11 | 27.8±4.1 | 28.3±4.14 | 0.49 |
| Pre-waist (cm) | 86.2±10.4 | 84.8±10.8 | 88±9.1 | 0.06 |
| Post-weight (kg) | 79.6±12.6 | 78.5±12.3 | 81±13 | 0.24 |
| Post-BMI (kg/m2) | 29.3±4.06 | 28.9±3.82 | 29.9±4.30 | 0.18 |
| Post-waist (cm) | 86.4±10.4 | 84.8±10.7 | 86.6±9.67 | 0.03* |
| HADS-A | 7.04±3.10 | |||
| HADS-D | 6.35±2.58 | 4.49±1.64 | 8.74±1.24 | <0.001* |
| HL (n,%) | 18 (12.7) | 10 (12.5) | 8 (12.9) | 0.94 |
| CAD (n,%) | 6 (4.2) | 3 (3.8) | 3 (4.8) | 0.75 |
| Smoking (n,%) | 43 (30.3) | 23 (28.7) | 20 (32.3) | 0.65 |
| Beta-blocker (n,%) | 37 (26.1) | 19 (23.8) | 18 (29) | 0.47 |
| Dihidropiridin CaCB (n,%) | 80 (56.3) | 42 (52.5) | 38 (61.3) | 0.29 |
| Non-dihidropiridin CaCB (n,%) | 11 (7.7) | 7 (8.8) | 4 (6.5) | 0.61 |
| ACEI-ARB (n,%) | 121 (85.2) | 70 (87.5) | 51 (82.5) | 0.38 |
| Alfa-blocker (n,%) | 16 (11.3) | 10 (12.5) | 6 (9.7) | 0.59 |
| Diuretic (n,%) | 93 (65.5) | 49 (61.3) | 44 (71) | 0.22 |
| Non dipper (n,%) | 59 (41.5) | 32 (40) | 27 (43.5) | 0.67 |
| Pre-Day SBP (mmHg) | 128±5.19 | 129±4.47 | 128±5.97 | 0.17 |
| Pre-Day DBP (mmHg) | 80.1±3.83 | 80.2±3.67 | 79.9±4.06 | 0.62 |
| Pre-Night SBP (mmHg) | 116±5.16 | 116±4.59 | 115±5.79 | 0.21 |
| Pre-Night DBP (mmHg) | 67.5±3.69 | 67.4±2.35 | 67.5±4.92 | 0.78 |
| Pre-24-h SBP (mmHg) | 124±5.55 | 125±4.44 | 124±6.69 | 0.16 |
| Pre-24-h DBP (mmHg) | 75.9±3.19 | 76.1±2.94 | 75.8±3.5 | 0.56 |
| Post-Day SBP (mmHg) | 135.2±6.87 | 132±5.51 | 139±6.22 | <0.001* |
| Post-Day DBP (mmHg) | 84.2±4.95 | 81.9±4.31 | 87.1±4.16 | <0.001* |
| Post-Night SBP (mmHg) | 120.4±5.80 | 118±5.37 | 123±5.35 | <0.001* |
| Post-Night DBP (mmHg) | 70.7±4.59 | 69±3.39 | 72.9±4.98 | <0.001* |
| Post-24-h SBP (mmHg) | 130.2±6.37 | 128±5.57 | 134±5.75 | <0.001* |
| Post-24-h DBP (mmHg) | 79.9±4.39 | 77.7±3.70 | 82.7±3.50 | <0.001* |
p<0.05
Abbreviations: BMI: body mass index; HADS-A: hospital anxiety and depression scale-anxiety; HADS-D: hospital anxiety and depression scale-depression; HL: hyperlipidemia; CAD: coronary artery disease; CaCB: calcium channel blocker; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; SBP: systolic blood pressure; DBP: diastolic blood pressure. Data were expressed as mean values ± SD or number (%) of patients.
The low HADS-A group consisted of hypertensive patients with an anxiety score<7, and the high HADS-A group consisted of hypertensive patients with an anxiety score of ≥7.