Table 1.

Comparison of our proposed SERS-LFA strip with other reported SAA/CRP detection methods.

Detection method	Analyte	LOD	Time	Reference
Protein microarrays	SAA	5.9 ng/mL	>2.5 h	Gul et al., 2007 [31]
SERS-LFA strip	CRP	0.01 ng/mL	20 min	Rong et al., 2018 [32]
Magnetoimmunosensor	CRP	8 ng/mL	20 min	Fernández et al., 2016 [33]
Fluorescent-LFA strip	CRP	0.5 ng/mL	15 min	Yang et al., 2020 [8]
SERS-LFA strip	SAA, CRP	0.1, 0.01 ng/mL	30 min	Liu et al., 2020 [6]
QD-based FLISA	SAA, CRP	2.39, 6.37 ng/mL	>1 h	Lv et al., 2019 [34]
SERS-LFA strip	SAA, CRP	0.1, 0.05 ng/mL	20 min	This work