Skip to main content
. 2021 May 27;14(6):518. doi: 10.3390/ph14060518

Table 4.

Log D7.4 (n-octanol/water) and effective passive permeability values (Peff) of complexes 1–3 at pH = 7.4. {T = 25.0 °C, 20 mM phosphate buffer}.

c(KCl) 1 2 3
logD7.4 4 mM −0.43 ± 0.09 n.d. +0.92 ± 0.06
logD7.4 24 mM −0.10 ± 0.05 n.d. +1.22 ± 0.04
logD7.4 100 mM +0.31 ± 0.03 n.d. +1.37 ± 0.06
Peff (cm/s) 100 mM 1.13 × 10−6 2.88 × 10−6 3.35 × 10−6
recovery 1.3% 15% 8.1%