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(a) Dependence of the size of nanogels prepared with different PLL-ciprofloxacin/alginate ratios at RT in deionized water; (b) size of the nanoparticles (PLL-ciprofloxacin/alginate 1/3) as a function of incubation time in phosphate buffer saline (pH 7.4) at 37 °C. The particle size for the 1/3 mixture here was somewhat higher because of the buffer and the higher temperature.
