Table 2.
DUBs | Inhibitors | References |
---|---|---|
USP7 | FT671 | [168] |
FT827 | [168] | |
GNE-6640 | [169] | |
GNE-6776 | [169] | |
HBX 19,818 | [170] | |
HBX 28,258 | [170] | |
HBX 41,108 | [171] | |
P22077 | [172] | |
P50429 | [173] | |
P5091 | [174,175] | |
vif1 | [176] | |
vif2 | [176] | |
XL177A | [177] | |
XL188 | [178] | |
USP19 | unknown | |
USP28 | AZ1 | [179] |
[1,2,3]triazolo[4,5-d]pyrimidine | [180] | |
USP37 | unknown | |
USP44 | unknown | |
OTUB2 | unknown | |
OTUD6B | unknown | |
OTUD7B | unknown | |
Broad spectrum DUB inhibitor | Betulinic acid | [181,182,183,184,185] |
PR-619 | [186,187] |