Table 1.
Characteristics of non-IRIS and IRIS patients.
| Parameters | All, n = 61 | HIV+, n = 46 (75%) | HIV+IRIS, n = 15, (25%) |
|---|---|---|---|
| Age (median) IQR | 34 (29–39) | 32 (29–39) | 36 (29–40) |
| CD4 count cells/ml, median (IQR) | |||
| Week 0 | 55 (31–105) | 54 (31–124) | 58 (25–101) |
| Week 4 post-ART | 151 (79–215) | 132 (75–214) | 165 (146–217) |
| Week 8 post-ART | 159 (117–252) | 158 (122–256) | 160 (113–215) |
| Week 12 post-ART | 164 (102–231) | 166 (104–247) | 160 (100–230) |
| Week 24 post-ART | 199 (152–274) | 204 (148–274) | 179 (161–274) |
| CD4/CD8 ratio, median (IQR) | |||
| Baseline | 0.07 (0.04–0.13) | 0.07 (0.04–0.13) | 0.08 (0.03–0.13) |
| Week 4 post-ART | 0.14 (0.09–0.25) | 0.14 (0.10–0.25) | 0.13 (0.08–0.28) |
| Week 8 post-ART | 0.17 (0.1–0.25) | 0.17 (0.11–0.24) | 0.14 (0.09–0.25) |
| Week 12 post-ART | 0.17 (0.11–0.26) | 0.18 (0.12–0.27) | 0.15 (0.11–0.22) |
| Week 24 post-ART | 0.21 (0.14–0.29) | 0.21 (0.14–0.28) | 0.20 (0.12–0.31) |
| HIV Viral load, Log10 copies/ml, median (IQR) | |||
| Baseline | 5.57 (5.1–5.8) | 5.5 (5.1–5.8) | 5.8 (5.2–6.0) |
| Week 4 post-ART | 2.8 (2.6–3.1) | 2.8 (2.6–3.1) | 2.8 (2.5–3.1) |
| Week 8 post-ART | 2.2 (1.6–2.6) | 2.2 (1.8–2.6) | 2.0 (1.6–2.6) |
| Week 12 post-ART | 1.8 (1.6–2.6) | 1.9 (1.6–2.6) | 1.7 (1.6–2.6) |
| Week 24 post-ART | 1.6 (1.6–1.6) | 1.6 (1.6–1.6) | 1.6 (1.6–1.6) |
Mann–Whitney U test was performed between HIV+ vs. HIV+IRIS groups.