Table 4.
(Protected) thiol-containing active esters (N-hydroxysuccinimide esters) for thiolation of multiamino polymers and chemical structure of the reactive acetimidate isopropyl (acetylthio)acetimidate (i-PATAI). Reagents used for Reactions 3 and 4 in Figure 8.
| Reaction Code | Compound | Ref. | Reaction Code | Compound | Ref. | ||
|---|---|---|---|---|---|---|---|
| Formula | Abbrev. | Formula | Abbrev. | ||||
| 3 |
 N-Succinimidyl-S-acetylthiopropionate |
SATP | [60] | 3 |
 N-Succinimidyl 3-(2-pyridyldithio) propionate |
SPDP | [55,93] |
| 3 |
 N-Succinimidyl S-(acetyl) thioglycolate |
SATA | [80,123] | 3 |
 N-Sulfosuccinimidyl 6-(3-(pyridin-2-yldisulfaneyl) propionamido) hexanoate |
Sulfo-LC-SPDP | [122,124] |
| 3 |
 NAC activated |
-- | [125] | 3 |
 GSH activated |
-- | [60] |
| 4 |
 Isopropyl (acetylthio)acetimidate |
i-PATAI | [95,121] | ||||