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. 2021 Jun 8;9(6):660. doi: 10.3390/biomedicines9060660

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The comparison between mac-2 binding protein glycosylation isomer (M2BPGi) levels between patients who developed hepatocellular carcinoma (HCC) or not (A) and receiver operating characteristics analysis regarding the cutoff of M2BPGi levels for the development of HCC (B) after the start of daclatasvir + asunaprevir among the cases without HCC history. According to the Youden index, the best cutoff of M2BPGI levels was 1.75 (sensitivity: 1.0, specificity: 0.66, positive predictive value: 0.333, negative predictive value: 1.0, diagnostic accuracy: 0.709). Area under the curve was 0.79 (95% confidence interval: 0.663–0.917).