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. 2021 Jun 9;57(6):594. doi: 10.3390/medicina57060594

Table 2.

Subgroup analysis on the association between PCT and the severity of COVID-19.

Subgroup Number of Study Pooled Effects (95% CI) I2 (%) P
All studies 10 1.77 (1.38–2.29) 85.6 0.000
Effect estimate
OR 6 1.65 (1.18–2.31) 75.0 0.001
HR 4 2.16 (1.21–3.84) 92.7 0.000
Sex (male, %)
≥55 5 1.90 (1.28–2.83) 86.3 0.000
<55 4 1.81 (1.09–3.00) 89.4 0.000
NA 1 9.33 (0.96–90.63)
Sample size
≥500 6 2.47 (1.55–3.94) 86.6 0.000
<500 4 1.16 (0.93–1.45) 63.4 0.042
Outcomes
Death 9 1.66 (1.29–2.14) 85.1 0.000
others 1 2.77 (1.57–4.89)
Age
≥60 6 1.68 (1.25–2.25) 82.4 0.000
<60 3 2.73 (0.75–9.88) 91.6 0.000
NA 1 9.33 (0.96–90.63)
Diabetes
1 3 1.23 (1.06–1.44) 50.7 0.132
0 7 3.20 (1.59–6.45) 89.6 0.000
Hypertension
1 3 1.40 (0.94–2.08) 81.9 0.004
0 7 2.31 (1.52–3.51) 86.8 0.000