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. 2021 May 27;13(6):998. doi: 10.3390/v13060998

Table 2.

Effect of BA treatment on VLP * binding to PGM.

Genotype Accession Number GCDCA Effect on Binding
GI.1 M87661 No effect
GI.2 FJ515294 No effect
GI.4 GQ413970 No effect
GI.5 KJ402295 No effect
GI.6 KC998959 No effect
GI.7 JN005886 No effect
GI.8 GU299761 No binding +/−GCDCA
GII.1 JN797508 GCDCA permits binding
GII.2 AY134748 GCDCA permits binding
GII.3_2002 KF006265 No binding +/−GCDCA
GII.3_2004 ** AB365435 No effect
GII.4_Sydney JX459908 No effect
GII.5 AF414422 No effect
GII.6 GU930737 No effect
GII.7 KF006266 No effect
GII.8 AB039780 No effect
GII.9 DQ379715 No effect
GII.10 AF504671 No binding +/−GCDCA
GII.12 KF006267 GCDCA permits binding
GII.13 JN899242 Enhancement of binding
GII.14 GU594162 Enhancement of binding
GII.15 GQ856474 No binding +/−GCDCA
GII.17 DQ438972 No effect

* VLPs generated from baculovirus-expressed ORF2 + 3 + 3UTR. Previously unpublished data except for GII.3_2004 (**) published in Murakami et al., 2020 [1]. The PGM binding assays are performed as described in Murakami et al., 2020 [1].