Figure 5.

Clinical significance of seven target genes (CACNB2, IL34, CGNL1, CNTN3, GAS7, HOPX, and PBX1) according to TCGA-HNSC data analysis. (A) Kaplan–Meier curves of the 5-year overall survival rate according to the expression of each gene are presented. Low expression of all seven genes was significantly predictive of a worse prognosis in patients with HNSCC. Patients were divided into two groups according to the median miRNA expression level: high and low expression groups. The red and blue lines represent the high and low expression groups, respectively. (B) Kaplan–Meier curves of the 5-year disease free survival rate according to the expression of each gene are presented. Low expression of six genes other than CACNB2 was significantly predictive of a worse prognosis in patients with HNSCC.