Table 11. Tandem Reaction of Sonogashira Coupling and Thiol-yne Addition to Afford Trisubstituted Thiophenes107.
R1 | R2 | yield (%) |
---|---|---|
p-MeOC6H4 | Ph | 97 |
p-NCC6H4 | p-(CH3)3C6H4 | 91 |
2-thienyl | Ph | 90 |
p-MeC6H4 | ferrocenyl | 91 |
R1 | R2 | yield (%) |
---|---|---|
p-MeOC6H4 | Ph | 97 |
p-NCC6H4 | p-(CH3)3C6H4 | 91 |
2-thienyl | Ph | 90 |
p-MeC6H4 | ferrocenyl | 91 |