Table 3. Conversion between a Thiol-Containing Peptide and Various Electrophilic Alkynes in Aqueous Acetonitrile Mixtures⁶⁷.

		conversion (%)
R1	R2	H2O	pH = 8 buffer
–NHPh	H	<5	60
–OMe	H	30	100
–Ph	H	100	100
–CH2CH2Ph	H	100	100
–Ph	–C4H9	<5	100
–CH2CH2Ph	–C4H9	<5	100