Table 1.
The distributions of demographical characteristics and clinical parameters in 1195 controls and 1125 cases with OSCC.
| Variable | Controls (N = 1194) | Patients (N = 1231) | p-Value |
|---|---|---|---|
| Age (yrs) | 53.90 ± 10.03 | 55.53 ± 10.85 | |
| <55 | 565 (47.3%) | 574 (46.6%) | p = 0.733 |
| ≥55 | 629 (52.7%) | 657 (53.4%) | |
| Betel quid chewing | |||
| No | 995 (83.3%) | 303 (24.6%) | |
| Yes | 199 (16.7%) | 928 (75.4%) | p < 0.001 * |
| Cigarette smoking | |||
| No | 558 (46.7%) | 193 (15.7%) | |
| Yes | 636 (53.3%) | 1038 (84.3%) | p < 0.001 * |
| Alcohol drinking | |||
| No | 957 (80.2%) | 648 (52.6%) | |
| Yes | 237 (19.8%) | 583 (47.4%) | p < 0.001 * |
| Stage | |||
| I + II | 575 (46.7%) | ||
| III + IV | 656 (53.3%) | ||
| Tumor T status | |||
| T1 + T2 | 605 (49.1%) | ||
| T3 + T4 | 626 (50.9%) | ||
| Lymph node status | |||
| N0 | 804 (65.3%) | ||
| N1 + N2 + N3 | 427 (34.7%) | ||
| Metastasis | |||
| M0 | 1220 (99.1%) | ||
| M1 | 11 (0.9%) | ||
| Cell differentiation | |||
| Well differentiated | 174 (14.1%) | ||
| Moderately or poorly differentiated | 1057 (85.9%) |
Mann–Whitney U test was used between healthy controls and patients with oral cancer. * p-value < 0.05 as statistically significant.