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. 2021 Jun 9;26(12):3534. doi: 10.3390/molecules26123534

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of OLT1177 on left ventricular function and remodeling. The echocardiographic results at 3 days and 10 weeks post-MI surgery indicate that no significant differences were reported between the control group and both OLT-treated groups. (A,B) LVEDD and LVESD significantly increased in the control group and the OLT-treated mice. (C) The LVEF values recorded show a significant reduction in the control group and the OLT-treated mice. (D) The LV mass of the control group and of both OLT-treated groups also show a significant increase throughout the study. Each triangle corresponds to the value measured in each mouse. The values are expressed as the mean ± SEM.