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LVEF contractile reserve assessment at 10 weeks after the non-reperfused MI surgery shows that the mice treated with OLT1177 (3.75 g/kg and 7.50 g/kg) had a significant % increase in LVEF following the isoproterenol challenge, reflecting an increase in the β-adrenergic response/contractile reserve. Each triangle corresponds to the value measured in each mouse. The values are expressed as the mean ± SEM.
