Table 3.
Changes (Δ) in fasting insulin, glucagon, and area under the curve (AUC) from the Oral Glucose Tolerance Test regarding insulin (240 min), glucagon (240 min), and HOMA-IR calculations.
Experimental Diets | |||||||
---|---|---|---|---|---|---|---|
Control | Mild and Sweet | Bitter and Strong | between Groups | ||||
Changes a | p-Value b | Changes a | p-Value b | Changes a | p-Value b | p-Value c | |
Fasting insulin (pmol/L) | −1.99 ± 4.1 | 0.63 | −7.77 ± 2.8 | <0.01 | −9.0 ± 3.33 | <0.05 | 0.29 |
Fasting glucagon (pg/mL) | −2.25 ± 2.19 | 0.32 | −2.23 ± 1.73 | 0.21 | −2.17 ± 1.78 | 0.28 | 0.99 |
AUC insulin240 min, (pmol/L ∗ 240 min) † | −632.7 ± 3355 | 0.85 | −2795 ± 2777 | 0.32 | −7199 ± 3476 | < 0.05 | 0.21 |
AUC glucagon240 min (pg/mL ∗ 240 min) | 142.7 ± 561.3 | 0.80 | −159.5 ± 416.2 | 0.71 | −13.6 ± 524.3 | 0.98 | 0.92 |
HOMA-IR † | −0.13 ± 0.42 | 0.76 | −0.46 ± 0.23 | 0.06 | −1.05 ± 0.23 | <0.0001 | 0.057 |
a Data are presented as mean ± SEM. b Statistical calculations are within-group differences (paired t-test). c Statistical calculations are between group differences (ANOVA). † denotes use of non-normally distributed data and use of the Kruskal–Wallis test.