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. 2021 Jun 9;10(6):730. doi: 10.3390/pathogens10060730

Table 1.

Risk factors associated with spontaneous preterm birth.

Risk Factors OR 95% CI Reference
Second trimester cervical length ≤2.50 cm 6.9 4.3–11.1 [8]
Vaginal bleeding in third trimester 5.9 5.1–6.9 [6]
Short interval between pregnancies (<12 months) 4.2 3.0–6.0 [6]
Previous preterm birth with a single newborn 2.62 1.99–3.44 [8]
Vaginal bleeding in first trimester 2.0 1.7–2.3 [6]
Periodontal disease 2.0 1.2–3.2 [6]
Prior cervical conization 1.7 1.24–2.35 [6]
Age younger than 18 1.7 1.02–3.08 [6]
Low socioeconomic condition 1.66 1.06–2.61 [8]
1.75 1.65–1.86 [6]
Pregnancy with male fetus 1.51 1.02–2.24 [8]
Asymptomatic bacteriuria 1.5 1.2–1.9 [6]
Bacterial vaginosis 1.4 1.1–1.8 [6]
Family history of preterm birth 1.35 1.12–1.63 [8]
Maternal smoking 1.27 1.21–1.33 [8]
1.7 1.3–2.2 [6]