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. 2021 May 27;9(6):610. doi: 10.3390/biomedicines9060610

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of intraplantar injections of CFA in vehicle-treated animals on the levels of OEA and PEA in the dorsal hippocampus (A,B) and entorhinal cortex (C,D). Two-way ANOVA has shown a significant overall effect of CFA on the levels of OEA in the dorsal hippocampus (B). Post hoc analysis with Student Newman-Keuls test indicated that OEA levels were significantly higher in the ipsilateral dorsal hippocampus of the CFA-vehicle group compared to No-CFA counterparts (B; * p < 0.05, vs. no-CFA; d = −0.390). Data are expressed as means ± SEM (n = 7–8 rats per group).