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. 2021 Jun 8;9(6):620. doi: 10.3390/vaccines9060620

Figure 5.

Figure 5

Capsid specificity of selected VHHs and interference of 12S particles in capsid quantification in DAS-ELISAs. Titrations of untreated authentic particles (a,b,d,e,g–i) or untreated VLPs (c,f) and their 12S particles from four FMDV strains in selected DAS-ELISAs as indicated on top of each panel (VLPs are marked in red). Another titration was done with a 2-fold dilution series of untreated FMDV particles to which a constant amount of 2 µg/mL 12S particles was added to measure interference of 12S particles. VHHs that bind specifically to 146S of serotype A strains are colored green or purple by their CDR3 group. Mean and standard deviation of triplicate ELISAs are given.