Table 2.

Human Readouts vs. Automated Readouts for AVENUE. Many automated readouts were generated. This table demonstrates that there was a high correlation between manual readouts that most clearly correspond to the automated [MA1] readouts.

Reading Center Feature	Automated Feature	Spearman r
CENT RET THICK µm	Central subfield thickness IB RPE-to-ILM 0.5 mm min	0.84
CENT RET/LESION THICK µm	Central subfield thickness BM-to-ILM 0.5 mm min	0.79
CENT SUBFIELD THICK ILM-RPE µm	Central subfield thickness IB RPE-to-ILM 0.5 mm mean	0.93
CUBE VOL ILM-RPE mm 3.0 mm	Central subfield volume IB RPE-to-ILM 3.0 mm	0.90
LESION THICK µm	Central subfield thickness BM-to-ILM 3.0 mm max	0.83
PED THICK µm	C-scan height PED 3.0 mm	0.71
SUBRET FLUID THICK µm	C-scan height SRF 3.0 mm	0.61