ATMP |
Advanced therapeutic medicinal product |
BM |
Bone marrow |
CBT |
Cord blood transplantation |
DMSO |
Dimethyl sulfoxide |
DT |
Doubling time |
EBMT |
European Group for Blood and Marrow Transplantation |
EP |
European pharmacopeia |
FBS |
Fetal bovine serum |
FDA |
Food and drug administration |
FIFO |
First-in first-out |
GMP |
Good manufacturing practice |
GVHD |
Graft versus host disease |
HCT |
Hematopoietic cell transplantation |
HPL |
Human platelet lysate |
HSA |
Human serum albumin |
IDO |
Indolamine oxidase |
IFNγ |
Interferon gamma |
ISBT |
International society of blood transfusion |
ISCT |
International Society of Cellular Therapy |
IQ |
Installation qualification |
IV |
Intravenous |
LTCG |
Laboratory of Cell and Gene Therapy |
MLR |
Mixed Lymphocyte Reaction |
MSC |
Mesenchymal stem/stromal cells |
NaCl |
Sodium chloride |
NAT |
Nucleic amplification technique |
OQ |
Operational qualification |
PBMC |
Peripheral blood mononuclear cells |
PDL |
Population doubling level |
PDL-1 |
Programmed death ligand 1 |
PQ |
Performance qualification |
QA |
Quality assurance |
QC |
Quality control |
QP |
Qualified person |
SCM |
Serum-containing media |
SFM |
Serum-free media |
SOP |
Standard operating procedure |
TSE |
Transmission of spongiform encephalopathy |
URS |
User-specific specifications |