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. 2021 May 27;10(6):862. doi: 10.3390/antiox10060862

Figure 2.

Figure 2

Cardamonin suppressed the activities of MMP-2 and MMP-9 as well as the protein expression levels of MMP-1, MMP-3 and MMP-13 in human OA chondrocytes induced by IL-1β. (A,B) Gel images revealed the analysis of cardamonin effects on MMP-2 and MMP-9 activities of IL-1β insulted using gelatin zymography gel. (C–F) Protein expression levels of MMP-1, MMP-3 and MMP-13 in IL-1β -induced chondrocytes following treatment with 10 µM cardamonin for 24 h. MMP-1, MMP-3 and MMP-13 protein expression demonstrate the analysis of cardamonin effects with IL-1β treatment, and significantly reduced with cardamonin. All data comes from at least three independent experiments, and their significance were as follows: cardamonin group and the control group are indicated by an asterisk (*); cardamonin group and the IL-1β group are indicated by a hash symbol (#). *, # p < 0.05.