Table 3.
Vitamins | Structure | Example Source | Inducer | Model | Effect | Mechanism | Ref |
---|---|---|---|---|---|---|---|
Vitamin C | Kiwi fruit, lemons | Senescence marker protein-30-konckout | Mice | ↑ Physical performance | ↓ MuRF1, MAFbx ↓ Oxidative stress |
[56] | |
Vitamin D | Milk, meat | Immobilization | C57BL/6 mice | ↑ Muscle mass | ↓ Oxidative stress ↓ MuRF1, MAFbx |
[60] | |
Vitamin E | Soybean oil | Immobilization | Wistar rats | / | ↓ Oxidative stress | [62] | |
Aging | Human | ↑ Muscle mass/strength | / | [63] | |||
β-Carotene | Carrot | Denervation | ddY mice | ↑ Muscle mass | ↓ Oxidative stress ↓ MuRF1, MAFbx, USP14, USP19 |
[65] | |
Coenzyme Q10 | Sardine | Disuse | SD rats | ↑ Muscle cross section | ↑ Mitochondrial biogenesis ↓ MuRF1, MAFbx, FoxO3 |
[68] | |
Nicotinamide mononucleotide | Broccoli, avocado | Aging | C57BL/6N | ↑ Physical performance | ↑ Mtochondrial oxidative metabolism | [70] |
Abbreviation: MAFbx, Muscle atrophy F-box; MuRF1, Muscle RING-finger protein-1; USP 14, Ubiquitin-specific processing protease 14; USP 19, Ubiquitin-specific processing protease 19; FoxO3, Forkhead box O3; ↑, Increase or promote; ↓, Decrease or inhibit.