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. 2021 Jun 2;13(6):1914. doi: 10.3390/nu13061914

Table 10.

Other phytochemicals in the prevention of the muscle atrophy in vitro/vivo.

Others Structure Example Source Inducer Model Effect Mechanism Ref
α-Ketoglutarate graphic file with name nutrients-13-01914-i056.jpg / Corticosterone C57BL/6J mice ↑ Muscle mass ↓ MuRF1, MAFbx [154]
C2C12 cells ↑ Myotube size ↓ MuRF1, MAFbx [154]
Cinnamaldehyde graphic file with name nutrients-13-01914-i057.jpg Cinnamon H2O2 C2C12 cells ↑ Myotube diameter ↓ MuRF1, MAFbx
↓ Oxidative stress
[155]
Fucoxanthin graphic file with name nutrients-13-01914-i058.jpg Undaria pinnatifida Dexamethasone ICR mice ↑ Muscle mass ↓ Oxidative stress [156]

Abbreviation: H2O2, Hydrogen peroxide; MAFbx, Muscle atrophy F-box; MuRF1, Muscle RING-finger protein-1; ↑, Increase or promote; ↓, Decrease or inhibit.