Table 4.
Summary of SNP windows that explained >1% of genetic variance for untrimmed thigh weight, with a list of positional candidate genes for each SNP (≤0.50 Mbps).
| Trait * | Chr | QTL Region (Mbps) | SNP | Candidate Genes (≤0.50 Mbps from SNP) |
|---|---|---|---|---|
| UTW | 1 | 174.09–176.24 | rs81349662, rs80948504, rs343652685, rs80782484, rs327453220, rs332492531, rs80819153, rs81271780, rs342853895 rs81236950, rs326407187, rs320846990, rs80818307 | PRPF39, MIS18BP1, FANCM, RPL10L, U6, SNORD127, FKBP3, TOGARAM1, ENSSSCG00000039829, ENSSSCG00000043072, ENSSSCG00000043544, ENSSSCG00000047027, ENSSSCG00000049486 |
| UTW | 4 | 109.68–110.08 | rs80977079, rs80870756, rs80980343, rs81380241 | LRIF1, CD53, ENSSSCG00000006801, KCNA3, KCNA10, ENSSSCG00000006804, PROK1, SLC16A4, RBM15, KCNC4, SLC6A17, ALX3, STRIP1, AHCYL1, EPS8L3, GSTM3, GNAT2, GNAI3, GPR61, U6, DRAM2, ENSSSCG00000028425, CEPT1, AMPD2, ENSSSCG00000033730, CSF1, KCNA2, ENSSSCG00000037808, ENSSSCG00000040889, ENSSSCG00000041122, ENSSSCG00000042722, ENSSSCG00000043070, ENSSSCG00000043393, ENSSSCG00000046426, ENSSSCG00000049472, ENSSSCG00000051454, ENSSSCG00000051784 |
| UTW | 6 | 130.11–131.38 | rs81391496, rs81391505, rs81391507, rs81391515, rs81391518, rs80900111, rs81391526, rs81335828, rs81327100, rs81391487, rs81391501, rs81391472, rs81391555, rs81274576, rs81222864, rs81257397, rs321214830 | TTLL7, ADGRL2, U6, PRKACB, ENSSSCG00000044932, ENSSSCG00000046121, ENSSSCG00000046184, ENSSSCG00000048726, ENSSSCG00000051159, ENSSSCG00000051341 |
| UTW | 7 | 111.45–111.59 | rs80938538, rs80869539, rs80871598, rs80819115, rs80878413 | FOXN3, EFCAB11, TDP1, KCNK13, PSMC1, NRDE2, ENSSSCG00000041236 |
| UTW | 8 | 85.70–85.70 | rs81402068 | INPP4B, IL15, ZNF330, RNF150, ENSSSCG00000041112, ENSSSCG00000041153, ENSSSCG00000041450, ENSSSCG00000044609 |
| UTW | 9 | 0.07–0.38 | rs81411123, rs81411485, rs81338651, rs81407864, rs81409222, rs81409931, rs81310106, rs81412401, rs81270995, rs81223860 | TRIM66, DENND2B, ENSSSCG00000014569, NRIP3, ENSSSCG00000014575, TMEM9B, DENND5A, TMEM41B, ZNF143, SNORA23, IPO7, STK33, AKIP1, ENSSSCG00000036604, SNORA3A, ENSSSCG00000041869, ENSSSCG00000042439, ENSSSCG00000044344, ENSSSCG00000044464, ENSSSCG00000046669, ENSSSCG00000047065, ENSSSCG00000049636, ENSSSCG00000050234, ENSSSCG00000051028 |
| UTW | 11 | 22.85–35.11 | rs81430421, rs80950281, rs81430434, rs80927521, rs80853848, rs81430439, rs81289163, rs81232833 | TSC22D1, ENSSSCG00000009425, ENSSSCG00000009426, ENOX1, SMIM2, SERP2, ENSSSCG00000041790, ENSSSCG00000042078, ENSSSCG00000042342, ENSSSCG00000043875, ENSSSCG00000044032, ENSSSCG00000046910, ENSSSCG00000046928, ENSSSCG00000047563, ENSSSCG00000049260, ENSSSCG00000049729, ENSSSCG00000051361, ENSSSCG00000051718 |
| UTW | 13 | 180.18–180.18 | rs81284542 | NRIP1, USP25, ENSSSCG00000042337, ENSSSCG00000042532, ENSSSCG00000047968, ENSSSCG00000051574, ENSSSCG00000051785 |
| UTW | 15 | 17.57–18.00 | rs81451598, rs81478999, rs81326202, rs81478982, rs81318409, rs81478797, rs81306466, rs81226590, rs81277838 | ACMSD, TMEM163, MGAT5, ENSSSCG00000040294, ENSSSCG00000041827, ENSSSCG00000043458, ENSSSCG00000045091, ENSSSCG00000046082, ENSSSCG00000047029, ENSSSCG00000048606, ENSSSCG00000051576 |
| TTW | 1 | 195.00–196.54 | rs80904604, rs80795061, rs80956668, rs325632167, rs80968730, rs323807748, rs80862783, rs80841106 | GPHB5, ENSSSCG00000005121, TEK, IFT74, LRRC19, PLAA, RHOJ, SNORD22, PPP2R5E, ssc-mir-9832, KCNH5, U6, ENSSSCG00000044869, ENSSSCG00000051292 |
| TTW | 4 | 109.58–110.25 | rs80953333, rs80977079, rs80945484, rs80870756, rs80980343, rs80826014, rs80926926, rs80882383, rs81380241, rs80960195 | CHI3L2, LRIF1, CD53, ENSSSCG00000006801, KCNA3, KCNA10, ENSSSCG00000006804, PROK1, SLC16A4, RBM15, KCNC4, SLC6A17, ALX3, STRIP1, AHCYL1, EPS8L3, GSTM3, GNAT2, GNAI3, GPR61, CYB561D1, ATXN7L2, SYPL2, PSMA5, SORT1, U6, DENND2D, DRAM2, ENSSSCG00000028425, CEPT1, AMPD2, ENSSSCG00000033730, AMIGO1, CSF1, KCNA2, ENSSSCG00000037808m ENSSSCG00000040889, ENSSSCG00000041122, ENSSSCG00000042722, ENSSSCG00000043070, ENSSSCG00000043393, ENSSSCG00000046426, ENSSSCG00000049472, ENSSSCG00000050471, ENSSSCG00000051040, ENSSSCG00000051454, ENSSSCG00000051784 |
| TTW | 5 | 19.82–19.88 | rs80818243, rs80800107 | HNRNPA1, NFE2, COPZ1, ENSSSCG00000000291, ZNF385A, ITGA5, NCKAP1L, ENSSSCG00000000296, PDE1B, PPP1R1A, TESPA1, ENSSSCG00000000312, MIR148B, U6, SMUG1, GTSF1, ENSSSCG00000033014, ENSSSCG00000033458, ENSSSCG00000034158, NEUROD4, ENSSSCG00000036953, ENSSSCG00000037462, OR10A7, CBX5, ENSSSCG00000040626, ENSSSCG00000041361, ENSSSCG00000044790, ENSSSCG00000047339, ENSSSCG00000048196, ENSSSCG00000048965, ENSSSCG00000049332, ENSSSCG00000050900, ENSSSCG00000050921, ENSSSCG00000051005 |
| TTW | 6 | 19.73–20.04 | rs81391898, rs81391786, rs334905777, rs81391709, rs81252955, rs81218446, rs81344881 |
CNOT1, GINS3, CCDC113, CSNK2A2, CFAP20, MMP15, USB1, ZNF319, TEPP, ENSSSCG00000002811, KIFC3, KATNB1, ADGRG3, ADGRG1, DRC7, PLLP, CCL22, ENSSSCG00000018402, SNORA50A, U6, NDRG4, CCL17, ENSSSCG00000024759, COQ9, POLR2C, ADGRG5, SETD6, PRSS54, CCDC102A, DOK4, CIAPIN1, GOT2, ENSSSCG00000037660, SLC38A7, ENSSSCG00000041797, ENSSSCG00000043194, ENSSSCG00000045991, ENSSSCG00000048393, ENSSSCG00000051066 |
| TTW | 6 | 130.11–134.84 | rs80930038, rs81391472, rs81391496, rs81391501, rs81391505, rs81391507, rs81327100, rs81274576, rs81335828, rs81222864, rs321214830, rs80900111, rs81391518, rs81391515, rs81257397, rs81391526, rs81391555, rs338651373, rs325952161, rs81391813, rs81278099, rs81340135, rs81347953, rs81306200 | TTLL7, ADGRL2, ADGRL4, IFI44, DNAJB4, NEXN, FUBP1, U6, IFI44L, GIPC2, PTGFR, PRKACB, ENSSSCG00000044932, ENSSSCG00000046121, ENSSSCG00000046184, ENSSSCG00000048726, ENSSSCG00000050806, ENSSSCG00000051159, ENSSSCG00000051341 |
| TTW | 7 | 111.36–111.66 | rs80938538, rs80812481, rs80826832, rs80793518, rs80869539, rs80871598, rs80898146, rs80819115, rs326024106, rs80878413 | FOXN3, EFCAB11, TDP1, KCNK13, PSMC1, NRDE2, CALM1, ENSSSCG00000041236, ENSSSCG00000046875, ENSSSCG00000051310 |
| TTW | 11 | 22.85–22.97 | rs81430421, rs81430434, rs80853848, rs81430439, rs81289163 | TSC22D1, ENSSSCG00000009425, ENSSSCG00000009426, ENOX1, SMIM2, SERP2, ENSSSCG00000041790, ENSSSCG00000042078, ENSSSCG00000042342, ENSSSCG00000044032, ENSSSCG00000046910, ENSSSCG00000046928, ENSSSCG00000047563, ENSSSCG00000049260, ENSSSCG00000049729, ENSSSCG00000051361 |
| TTW | 15 | 17.57–18.00 | rs81451598, rs81478999, rs81326202, rs81478982, rs81318409, rs81478797, rs81306466, rs81226590, rs81277838 | ACMSD, TMEM163, MGAT5, ENSSSCG00000040294, ENSSSCG00000041827, ENSSSCG00000043458, ENSSSCG00000045091 ENSSSCG00000046082, ENSSSCG00000047029, ENSSSCG00000048606, ENSSSCG00000051576 |
* UTW, Untrimmed thigh weight; TTW, Trimmed thigh weight.