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Diagram of choroidal neovascularization. (A). Normally, the Bruch’s membrane and the retinal pigment epithelium separate the neuroretina from the choroid. (B). Disturbances in homeostasis result in the formation of abnormal blood vessels that overgrow Bruch’s membrane and spread under the pigment epithelium and in the subretinal space, causing neuroretina elevation and swelling.
