Table 3.

A summary of the identified associations of Eph and ephrins with proliferative vitreoretinopathy.

Name	Established Association with Proliferative Vitreoretinopathy	Possible Mechanism	Possible Use in Clinical Practice	Reference
ephrinB2 and EphB4	Expression in PVR membranes	Effect on migration and transdifferentiation of RPE cells	Potential therapeutic target	[63]
EphB4	Reduction of PDGF-induced migration and proliferation of RPE cells by the soluble form of EphB4	Reduction in FAK and p42/44 MAPK dependent phosphorylation	Potential therapeutic target	[69]