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. 2021 Jun 25;51:9. doi: 10.1186/s42649-021-00058-7

Table 1.

Summary of the NIR organic dyes

Class Name Ex. Emi. Abs. Q.Y. Biomedical Applications Ref.
Polymethine (Cyanine) Cy3 550 570 309 0.15 Biotechnologies (labeling, analysis, biomedical imagings)
Cy5 650 670 409 0.27
Cy7 743 767 512 0.28
ICG 788 830 800 0.04 Clinical angiography, laparoscopic surgery Kim et al. 2018
CDnir7 806 821 0.14 Bioimaging – inflammation Kang et al. 2014
TiNIR 805 825 0.09 Bioimaging - lung tunor initiating cells Kim et al. 2019b
Polymethine (Sulfur) IR-26 785, 808 ~ 1050 950 ~ 0.05 Bioimaging - Lymphatic systems Wang et al. 2019
IR-1061 980 1074 ~ 1000 ~ 0.02 Bioimaging - Inner organs and blood vessels Tao et al. 2013
IRBTP-B 950 ~ 1000 905 0.001 Detection - drug-induced hepatotoxicity Zhao et al. 2021
D-A-D (benzobisthadiazoles) H1 785 ~ 1100 600–1000 0.02 Biomaging - tumor; Imaging-guided surgery Sun et al. 2017
Q8 808 1020–1150 600–1000 0.0001 Bioimaging - tumor, Imaging-guided surgery Qu et al. 2019
IR-FP8 808 ~ 1000 808 0.04 Videorate imaging - hindlimb vessels of mice Ma et al. 2020
TPB-AZO 909 690 0.22 Detection - cardiac cyle and heart rate Zhang et al. 2020
BPST 715 897 347–711 0.06 Bioimaging - blood, lymphatic vessels, and tumors Wu et al. 2019
HLZ-BTED 785 ~ 1000 ~ 805 0.002 Detection - gastrointestinal function and diseases Lin et al. 2019
XA1 808 ~ 1000 400–780 0.15 Bioimaging - limb and cerebral vessels Xu et al. 2020
2TT-oC6B 808 1014 700 0.11 Bioimaging - brain inflammation Liu et al. 2020