Figure 3.

Dose-dependent effect of SMs, antibody and peptides on SRAE2-BS activity. (A–C) Increasing concentrations of SMs (A), IgG (control) or VHH72 anti-RBD antibody (B), or ACE2-P1-P2 peptides (C) were preincubated with RBD-Lg-His, and subsequently incubated with Sm-ACE2-His for 30 min, followed by measurement of RLU. (D) Increasing concentration of RBD-P1-P3 peptides were preincubated with Sm-ACE2-His, and subsequently incubated with RBD-Lg-His, followed by measure of RLU. The mean +/− standard error (S.E.) of relative values (relative to control) of triplicate samples were calculated in comparison to samples without treatment (control).