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CF accumulation in the presence of glutathione. ABCC-like activity was evaluated by the CF efflux assay in the presence of 5 mM of GSH or GSSG. (A) Representative histograms, (B) CF MFI, (C) percentage of CF+ parasites, and (D) inhibition index compared to control (CTL) from the Y strain. Lines represent the median, bars represent mean + SEM, and the values of significance were represented by (*) for p < 0.05, (**) p < 0.01, and (***) p < 0.001, n = 8 independent experiments.
