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. 2021 Jun 9;26(12):3510. doi: 10.3390/molecules26123510

Figure 6.

Figure 6

CF accumulation in the presence of the inhibitor MK-571 in T. cruzi sensitive and resistant to benznidazole. ABCC-like activity was evaluated by the carboxyfluorescein (CF) efflux assay in the presence of 200 μM MK-571. Graphs exhibit CF MFI (left panel) and percentages of CF+ parasites (right panel) from (A,B) CL Brener, (C,D) Berenice, (E,F) Colombiana strains, and (G,H) Y-RBz parasites. Lines represent the median and values of significance were represented by (**) for p < 0.01, n = 9 independent experiments.