Figure 4.

Apoptotic effects of ISDPs in Candida albicans SC5314 cells. Phosphatidylserine externalization was analyzed by flow cytometry, after 30 min of treatment with peptides at their double EC₅₀ value. Data represent the mean ± standard deviation from at least two independent experiments. The percentage of apoptotic cells after treatment with R10S-RR, although low, was significantly different from that of untreated (control, black *) or parent peptide-treated (red *) cells, as assessed by Student’s t-test (p < 0.05).