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In vitro candidacidal activity of in silico designed peptides (ISDPs) against C. albicans SC5314.
| Peptide | EC50 1 (95% Confidence Intervals) | EC50 ISDP/EC50 K10S |
|---|---|---|
| K10S | 0.277 (0.274–0.279) 2 | - |
| R10S-RR | 0.254 (0.247–0.262) | 0.92 |
| K10T-TT | 0.173 (0.171–0.175) | 0.62 |
| K10S-SS | 0.159 (0.150–0.168) | 0.57 |
| K10S-I | 0.260 (0.239–0.282) | 0.94 |
1 EC50, half maximal effective concentration, [mol/liter] × 10−6; 2 EC50 of K10S parent peptide [19].
