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Representative curves of thrombin-catalyzed fibrin polymerization and fibrinolysis. ACS: patients with acute coronary syndrome; SCAS: patients with significant carotid artery stenosis; AIS: patients with acute ischemic stroke; control: patients with normal angiogram. Clot degradation was measured at 350 nm after addition of thrombin (12 NIH U/mL), plasminogen (0.15 NIH U/mL), tPA (0.3 µg/mL) and CaCl2 (8 mM).
