Table 1.
Patient Group Descriptions | ACS | SCAS | AIS | Control | p-Value |
---|---|---|---|---|---|
(n = 10) | (n = 10) | (n = 10) | (n = 10) | ||
Demographic and risk factors | |||||
Age | 60.0 (47.0–70.0) | 69.5 (65.0–79.0) | 73.5 (69.0–86.0) | 69.0 (51.0–77.0) | 0.02 1 |
Sex female/male | 3/7 | 4/6 | 3/7 | 7/3 | 0.22 2 |
Diabetes mellitus | 3 | 7 | 4 | 2 | 0.12 2 |
Active smoking | 5 | 4 | 1 | 2 | 0.19 2 |
Arterial hypertension | 6 | 7 | 8 | 8 | 0.50 2 |
Dyslipidemia | 2 | 9 | 3 | 6 | 0.01 2 |
BMI (mean ± SD) | 28.07 ± 4.10 | 26.85 ± 4.06 | 30.26 ± 5.24 | 30.57 ± 4.49 | 0.21 1 |
Pre-admission antithrombotic treatment | |||||
Acetylsalicylic acid | 2 | 5 | 3 | 4 | |
Clopidogrel | 0 | 5 | 1 | 0 | |
Fraxiparine | 0 | 1 | 0 | 0 | |
DOACs | 0 | 0 | 0 | 2 | |
Warfarin | 0 | 0 | 0 | 1 | |
Pre-admission dyslipidemic treatment | |||||
Statins | 2 | 9 | 3 | 6 | |
Fenofibrate | 0 | 0 | 0 | 1 | |
Previous coronary events | |||||
Percutaneous coronary intervention | 1 | 0 | 1 | 0 | |
Myocardial infarction | 2 | 1 | 2 | 0 | |
Coronary artery bypass graft | 0 | 0 | 2 | 0 | |
Ischemic stroke | 0 | 5 | 10 | 0 | |
Peripheral artery disease | 0 | 4 | 2 | 0 | |
Clinical presentation | |||||
Triacylglycerols (mM) | 0.95 (0.76–1.31) | 1.49 (1.00–1.72) | 1.10 (0.61–2.18) | 0.99 (0.64–1.13) | 0.08 1 |
Total cholesterol (mM) | 4.50 (3.87–5.44) | 4.52 (3.19–4.95) | 4.21 (2.32–5.40) | 3.85 (3.48–5.15) | 0.92 1 |
High density lipoproteins (mM) | 1.03 (0.84–1.42) | 1.36 (0.96–2.07) | 0.96 (0.84–1.41) | 1.44 (1.03–1.90) | 0.08 1 |
Low density lipoproteins (mM) | 3.04 (2.01–3.64) | 2.00 (1.53–2.82) | 2.58 (0.92–3.65) | 2.13 (1.62–3.06) | 0.31 1 |
Glycosylated hemoglobin (mmol/mol) | 40.5 (36.0–96.0) | 50.5 (40.0–69.0) | 39.0 (33.0–57.0) | 39.0 (37.0–54.0) | 0.13 1 |
ACS: acute coronary syndrome; SCAS: significant carotid artery stenosis; AIS: acute ischemic stroke; BMI: body mass index; SD: standard deviation; NA: not available. Values are given as mean ± SD, median 5–95th percentiles in parentheses. 1 Kruskal–Wallis test, 2 Chi-square.