Table 2.

Mycotoxins’ dissociation constants, experimental (logP) and computed polarity (XlogP3-AA) according to literature data, and average transfer rate into infusion.

Mycotoxin		pKa	logP	XlogP3-AA [37]	Transfer, %
AFL B1	neutral	17.8 [38]	0.45 [38]	1.6	33 ± 3
AFL B2	neutral			1.3	41 ± 5
AFL G1	neutral			1.8	34 ± 9
AFL G2	neutral			1.5	47 ± 6
STC	neutral			3.4	12 ± 2
OTA	amphoteric	3.29/−2.20 [38]	4.4 (pH 3)/1.1 (pH 7) [38]	4.7	38–80 *
MPA	acidic	4.2 [39]		3.2	38–86 *
DONDW,D-WW	neutral	11.91 [38]	−1.41 (pH 3)/−1.41 (pH 7) [38]	−0.7	83 ± 5
DONNMW					70 ± 5
ZEA	acidic	7.41 [38]	3.83(pH 3)/3.72 (pH 7) [38]	3.6	15 ± 3
FB1	amphoteric	3.64/9.29 [38]	−0.61 (pH 3)/−3.23 (pH 7) [38]	−0.5	89 ± 10
FB2	amphoteric	3.64/9.25 [38]	1.58 (pH 3)/−1.04 (pH 7) [38]	1.2	40–103 *
HT-2	neutral	13.26 [38]	2.27 (pH 3)/2.27 (pH 7) [38]	0.4	78 ± 14
T-2	neutral	13.23 [38]	2.25 (pH 3)/2.25 (pH 7) [38]	0.9	71 ± 8
ALT	acidic	7.5 [40]	0.87 [40]	0.7	67 ± 8
TE	acidic	5.33 [40]	1.21 [40]	2	73 ± 9
AOH	acidic	7.16 [38] 7.63 [40]	3.03 (pH 3)/3.06 (pH 7) [38] 3.18 [40]	2.9	18 ± 4
AME	acidic	6.99 [38] 7.71 [40]	3.93 (pH 3)/3.62 (pH 7) [38] 3.32 [40]	3.2	<12.5 **
ENN BDW	basic	−1.08 [38]	3.05 (pH 3)/3.05 (pH 7) [38]	6.5	12 ± 4
ENN BD-WW,NMW				6.5	<3 **
ENN A	basic	−0.96 [38]	4.64 (pH 3)/4.64 (pH 7) [38]	7.6	<5 **
BEA	neutral	18.8 [38]	5.5 (pH 3)/5.5 (pH 7) [38]	8.4	<5 **

*—transfer is pH-dependent; **—were not quantified in infusions (maximum transfer evaluated using LOQ).