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(A) Color change as measured by ΔE* in both water and feed upon addition of degradation products. Solutions of degradation products in DMSO were spiked into aqueous solutions to yield a theoretical concentration of 500 µM (1% DMSO). (B) Toxicity data for the Trp degradation products that produced a significant toxicity in CHOK1 GS cells as compared to the DMSO control. Error bars, S.D.
