Table 1.
The low-grade coeliac scoring system (−2 to 25 points): a score >10 points is considered positive [18].
| Predictors | Points |
|---|---|
| Serum anti-tTG2 | |
| >20 U/mL | 10 |
| >8–20 U/mL or >2–8 U/mL plus EmA+ | 6 |
| >2 to 8 U/mL plus EmA- | 2 |
| 2 U/mL | 0 |
| IEL cytometry pattern | |
| ↑TCRγδ+ cells | 7 |
| Histology (IEL count) | |
| >25% | 5 |
| 19–25% | 0 |
| <19% | −1 |
| Coeliac genetics: | |
| DQ2.5+ | 3 |
| DQ8+/DQ2.2+/Allele DQB1 of haplotype DQ2.5+ | 0 |
| 2 alleles DQ2.5- and DQ8- | −1 |
Serum anti-tTG2: IgA anti-transglutaminase antibodies; EmA: IgA anti-endomysium antibodies; IEL: intraepithelial lymphocytes.