Table 4.
Model | k1 (min−1) | k2 (L mg−1min−1) | R² | χ² | AIC |
---|---|---|---|---|---|
Simulated gastric fluid (25 °C) | |||||
Pseudo-first-order | 0.0301 | - | 0.793 | 5.64 × 10−6 | −73.66 |
Pseudo-second-order | - | 2.267 | 0.848 | 4.14 × 10−6 | −75.68 |
Simulated intestinal fluid (25 °C) | |||||
Pseudo-first-order | 0.604 | - | 0.820 | 2.02 × 10−6 | −51.74 |
Pseudo-second-order | - | 57.769 | 0.889 | 1.24 × 10−6 | −54.02 |
Simulated gastric fluid (37 °C) | |||||
Pseudo-first-order | 0.024 | - | 0.891 | 2.75 × 10−6 | −67.24 |
Pseudo-second-order | - | 1.818 | 0.907 | 2.34 × 10−6 | −68.15 |
Simulated intestinal fluid (37 °C) | |||||
Pseudo-first-order | 0.067 | - | 0.881 | 1.41 × 10−6 | −59.32 |
Pseudo-second-order | - | 10.919 | 0.949 | 5.98 × 10−7 | −63.42 |