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. 2021 Jun 7;13(6):842. doi: 10.3390/pharmaceutics13060842

Table 4.

Fitting parameters of the pseudo-first- and pseudo-second-order kinetic models for the release of MB from the chitosan/pectin blend hydrogel in different fluids.

Model k1 (min−1) k2 (L mg−1min−1) χ² AIC
Simulated gastric fluid (25 °C)
Pseudo-first-order 0.0301 - 0.793 5.64 × 10−6 −73.66
Pseudo-second-order - 2.267 0.848 4.14 × 10−6 −75.68
Simulated intestinal fluid (25 °C)
Pseudo-first-order 0.604 - 0.820 2.02 × 10−6 −51.74
Pseudo-second-order - 57.769 0.889 1.24 × 10−6 −54.02
Simulated gastric fluid (37 °C)
Pseudo-first-order 0.024 - 0.891 2.75 × 10−6 −67.24
Pseudo-second-order - 1.818 0.907 2.34 × 10−6 −68.15
Simulated intestinal fluid (37 °C)
Pseudo-first-order 0.067 - 0.881 1.41 × 10−6 −59.32
Pseudo-second-order - 10.919 0.949 5.98 × 10−7 −63.42