Table 2.
Drug susceptibility testing by fluorescence-based neuraminidase inhibition assay.
| Viruses | Subtypes | Passage No. of Isolate | Mean IC50 ± SD (nM) |
|---|---|---|---|
| A/Thailand/TM-18334_61/2018 | H1N1 | 1,2,3 | 0.59 ± 0.07 |
| A/Thailand/TM-3627_55/2018 | H1N1 | 5,6,7 | 0.29 ± 0.08 |
| A/Thailand/TM-12108_51/2019 | H1N1 | 7,8,9 | 0.23 ± 0.05 |
| A/Thailand/TM-6375_40/2019 | H1N1 | 3,4,5 | 0.48 ± 0.07 |
| A/Thailand/TM-4042_61/2019 | H1N1 | 3,4,5 | 0.16 ± 0.01 |
| A/Thailand/TM-3418_56/2019 | H1N1 | 2,3,4 | 0.35 ± 0.04 |
| A/Thailand/TM-13108_62/2018 | H1N1 | 1,2,3 | 0.57 ± 0.01 |
| B/Thailand/TM-6610_57/2019 | B/Vic | 3,4,5 | 33.96 ± 4.12 |
| B/Thailand/TM-3038_62/2019 | B/Vic | 1,2,3 | 40.10 ± 0.91 |
| B/Thailand/TM-12875_57/2019 | B/Vic | 2,3,4 | 23.38 ± 2.76 |
| B/Thailand/TM-2580_62/2019 | B/Vic | 3,4,5 | 17.18 ± 3.38 |
| B/Thailand/TM-2953_55/2019 | B/Vic | 1,2,3 | 36.84 ± 5.28 |
| B/Thailand/TM-10944_62/2019 | B/Vic | 2,3,6 | 22.62 ± 1.15 |
| A/Thailand/TM-8453_54/2018 | H3N2 | 2,3,4 | 0.41 ± 0.04 |
| A/Thailand/TM-17617_61/2018 | H3N2 | 6,7,8 | 0.14 ± 0.02 |
| A/Thailand/TM-12054_56/2019 | H3N2 | 8,9,10 | 0.21 ± 0.04 |
| A/Thailand/TM-12909_43/2019 | H3N2 | 4,5,6 | 0.11 ± 0.02 |
| A/Thailand/TM-358_60/2018 | H3N2 | 7,8,9 | 0.05 ± 0.01 |
| A/Thailand/TM-54_54/2018 | H3N2 | 6,7,8 | 0.11 ± 0.01 |
| A/Thailand/TM-5434_51/2019 | H3N2 | 5,6,7 | 0.06 ± 0.01 |
| A/Mississippi/03/01 wt (274H) | H1N1 | 6 | 0.67 ± 0.03 |
| A/Mississippi/03/01mutant 274Y | H1N1 | 6 | 286.01 ± 14.02 |
| A/Fukui/45/04 wt (119E) | H3N2 | 5 | 0.23 ± 0.02 |
| A/Fukui/45/04 mutant (119V) | H3N2 | 5 | 30.66 ± 0.88 |