Figure 1.
mRNA and protein overexpression of HDAC6 and mesenchymal markers in GBM samples. (A) RT-qPCR for HDAC6 and mesenchymal markers Snail and Slug in parietal and temporal lobe as well as GBM tissue. Data are represented as mean ± SD. (*) p < 0.05, (**) p < 0.01 vs. temporal lobe. (Temporal lobe: n = 7, parietal lobe: n = 7, GBM n = 11). (B) Western blot image for HDAC6, N-cadherin, and β-actin of control brain tissue and GBM tissue. (C) Analysis of western blot. Data are represented as mean ± SD. (*) p < 0.05, (**) p < 0.01 vs. temporal lobe, (⁰) p < 0.05, (⁰⁰) p < 0.01 vs. parietal lobe (temporal lobe: n = 7, parietal lobe: n = 7, GBM n = 10).